Keywords: Leardngam, Dysmenorrhea, Thai traditional medicine, Mefenamic acid, Leardngam, Randomized control trial
Setting:
Before the extensive use of modern medications, dysmenorrhea was traditionally treated with herbal remedies. In contrast, NSAIDs commonly produce gastrointestinal side effects in users. Although the Leardngam drug, a Thai traditional herbal medicine, has long been used to treat dysmenorrhea, it lacks clinical trial proof, which often causes healthcare providers to be hesitant to administer it. the randomized controlled trial was conducted to answer these questions.
Target group:
young adult female in Burapha university,
Description of the innovative practice or project:
A total of 240 college students were enlisted and randomized into six groups for the 2020–2021 academic year: Leardngam 1 and 2 (LG1 and LG2), Mefenamic acid 1 and 2 (MF1 and MF2), and placebo 1 and 2 (PB1 and PB2). To evaluate dysmenorrhea, a numerical rating system was employed. Throughout the experiment, all subjects were observed for patterns of menstruation and drug side effects
Evaluation:
menstrual pain relief, menstrual characteristics, adverse effects of each group.
Next Steps:
240 female college students were the participant in this study.
Lessons learned:
The average gaps of dysmenorrheal scores were statistically significant difference during three months (X2=97.13, p.01; X2=104.90, p.01; and X2=113.80, p.01, respectively). The multiple comparison discovered the pain gaps in placebo groups were statistically significant difference from others. The pain gaps in treatment groups were greater than placebo groups. However, these pain gaps between the Leardngam and mefenamic groups were not statistically significant. The mefenamic group had greater dyspeptic symptoms than the other groups, and the Leardngam group had a higher incidence of loose stool. Leardngam was as efficient as mefenamic acid at relieving menstrual pain, with fewer side effects.
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